Friday, October 9, 2009
Dosage regimen
Inside, about 1 hour before planned sexual activity. Single dose for adults - 50 mg 1 time per day. Given the efficacy and tolerability the dose may be increased to 100 mg or decreased to 25 mg. The maximum single dose - 100 mg. In patients with impaired liver or kidney function and elderly patients dose adjustment is required.
Contraindications
Hypersensitivity; simultaneous reception donor of nitric oxide or nitrates in any form. C carefully. Heart diseases, anatomical deformation of the penis, sickle cell anemia, multiple myeloma, leukemia, childhood.
Indications and application
Erectile dysfunction of various etiologies (organic, psychogenic, mixed). Impotence. Treatment of pulmonary hypertension.
In Israel, attempts were made to use sildenafil as drugs that enhance the portability of large loads in the army.
In Israel, attempts were made to use sildenafil as drugs that enhance the portability of large loads in the army.
How does Viagra in the clinical sense?
volunteers with varying degrees of erectile dysfunction. As shown by tests, Viagra has a high efficiency.
The effectiveness of Viagra in the first place depends on the degree of erectile dysfunction, as well as from its cause. For example, if the problem erektalnoy vascular dysfunction, the drug copes with its task.
If the problem lies in the venous drainage, the result of Viagra will be much worse.
As practice shows, does not exist and probably will not be a drug that can cure all diseases.
Yeah, Viagra really works and helps in most cases.
The effectiveness of Viagra in the first place depends on the degree of erectile dysfunction, as well as from its cause. For example, if the problem erektalnoy vascular dysfunction, the drug copes with its task.
If the problem lies in the venous drainage, the result of Viagra will be much worse.
As practice shows, does not exist and probably will not be a drug that can cure all diseases.
Yeah, Viagra really works and helps in most cases.
Thursday, October 8, 2009
History of discovery
Opening of the first of the drugs sildenafil issued under the patented name "Viagra" was probably the third greatest "accidental" discovery in medicine - after the discovery of X-rays and penicillin. These discoveries were awarded the Nobel Prize. The same high award in autumn 1998 were awarded to researchers who discovered, among other things, the properties of the drug "Viagra".
The history of "Viagra" has started in 1992 in the UK, in the town Pfayzers Sandwich, in the course of pharmaceutical research firm Pfizer. The researchers conducted clinical trials of a new drug substance - sildenafil citrate, which was developed as a means to treat certain heart ailments.
Scientists had hoped that sildenafil citrate will help to increase blood flow to the heart muscle and reduce blood pressure. However, it was observed that sildenafil citrate, has no significant effect either on blood circulation in the heart muscle (myocardium), or on blood pressure. At the same time revealed that many male patients who participated in the study refused to return the tablets sildenafil, despite the end of testing. The reason for failure in all these patients had one - they all pointed in his dramatic improvement in the quality of erections. Thus, despite the minimal impact of new drugs on blood circulation in the myocardium, sildenafil caused significant blood flow to male genitals.
Researchers at pharmaceutical company Pfizer took this unexpected property of sildenafil citrate with due attention and were able to recognize in it a powerful tool to combat erectile dysfunction. A new drug called "Viagra" - the name was born as a result of the merger would be the words "Vigor" (power, energy, force) and the Niagara - the most powerful waterfall in North America.
Since 1993 began extensive clinical trials necessary to demonstrate the properties of "Viagra". As a result of these tests proved the high effectiveness of Viagra for treating impotence and high safety of this drug. And as a logical final - March 27, 1998 U.S. Department of Food and Drug approved the use of "Viagra". The action of the drug "Viagra" evaluated more than 3000 men aged 19 to 87 years in studies of erectile dysfunction, held all over the world. Length erection disorders in these patients averaged 5 years (from 6 months to 26 years), and disorders of erection have been organic, psychogenic and mixed organic and psychogenic nature.
The results of these studies indicate that the drug "Viagra" is effective for restoration of erectile function and improve the performance of successful intercourse with a large number of patients, including at a number of diabetic patients with spinal cord injuries and other associated clinical conditions as well as in patients receiving simultaneously a number of medicines.
The history of "Viagra" has started in 1992 in the UK, in the town Pfayzers Sandwich, in the course of pharmaceutical research firm Pfizer. The researchers conducted clinical trials of a new drug substance - sildenafil citrate, which was developed as a means to treat certain heart ailments.
Scientists had hoped that sildenafil citrate will help to increase blood flow to the heart muscle and reduce blood pressure. However, it was observed that sildenafil citrate, has no significant effect either on blood circulation in the heart muscle (myocardium), or on blood pressure. At the same time revealed that many male patients who participated in the study refused to return the tablets sildenafil, despite the end of testing. The reason for failure in all these patients had one - they all pointed in his dramatic improvement in the quality of erections. Thus, despite the minimal impact of new drugs on blood circulation in the myocardium, sildenafil caused significant blood flow to male genitals.
Researchers at pharmaceutical company Pfizer took this unexpected property of sildenafil citrate with due attention and were able to recognize in it a powerful tool to combat erectile dysfunction. A new drug called "Viagra" - the name was born as a result of the merger would be the words "Vigor" (power, energy, force) and the Niagara - the most powerful waterfall in North America.
Since 1993 began extensive clinical trials necessary to demonstrate the properties of "Viagra". As a result of these tests proved the high effectiveness of Viagra for treating impotence and high safety of this drug. And as a logical final - March 27, 1998 U.S. Department of Food and Drug approved the use of "Viagra". The action of the drug "Viagra" evaluated more than 3000 men aged 19 to 87 years in studies of erectile dysfunction, held all over the world. Length erection disorders in these patients averaged 5 years (from 6 months to 26 years), and disorders of erection have been organic, psychogenic and mixed organic and psychogenic nature.
The results of these studies indicate that the drug "Viagra" is effective for restoration of erectile function and improve the performance of successful intercourse with a large number of patients, including at a number of diabetic patients with spinal cord injuries and other associated clinical conditions as well as in patients receiving simultaneously a number of medicines.
Sildenafil (Viagra)
Viagra - the commercial name of the drug, developed by U.S. company Pfizer, Syagrius, Dzhenagra, capacity, etc. - the commercial name of the drug, a significant proportion of drugs manufactured in India.
Sildenafil is available in tablet form for 25, 50 and 100 mg, which contain, respectively, at 25, 50 and 100 mg of sildenafil citrate.
The mechanism of action of Sildenafil: the drug increases the amount of blood flowing to the penis. This helps a man to call a natural erection. Sildenafil is effective only when a man experiencing a natural sexual arousal, and when the sexual act is completed, the penis naturally returns to the relaxed state. In other words, sildenafil acts only on natural mechanisms of erection and this is its undeniable novelty and secret huge popularity.
Sildenafil is available in tablet form for 25, 50 and 100 mg, which contain, respectively, at 25, 50 and 100 mg of sildenafil citrate.
Unlike other treatments for erectile dysfunction, which provide for injections into the penis or other medical procedures, sildenafil is a simple, convenient and easily used drug. Using sildenafil take one tablet before planned sexual intercourse.
The mechanism of action of Sildenafil: the drug increases the amount of blood flowing to the penis. This helps a man to call a natural erection. Sildenafil is effective only when a man experiencing a natural sexual arousal, and when the sexual act is completed, the penis naturally returns to the relaxed state. In other words, sildenafil acts only on natural mechanisms of erection and this is its undeniable novelty and secret huge popularity.
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